Total drugs in database: 34
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This demo uses a curated lite DrugBank subset, so search results and interaction coverage are intentionally limited.
| Drug Name | DrugBank ID | Type | Description | Categories | Actions |
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Amphetamine
(+-)-alpha-Methylphenylethylamine, 1-phenyl-2-aminopropane
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DB00182 | small molecule |
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used … |
Adrenergic Agents
Agents producing …
Agents that …
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Nicotine
(−)-nicotine, (S)-(−)-nicotine
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DB00184 | small molecule |
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and … |
Agents producing …
Alkaloids
Autonomic Agents
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Lorazepam
Loracepam, Lorazepam
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DB00186 | small molecule |
Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic.[A957] It was developed by DJ … |
Anti-Anxiety Agents
Anticonvulsants
Antiemetics
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Caffeine
1-methyltheobromine, 1,3,7-trimethyl-2,6-dioxopurine
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DB00201 | small molecule |
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the … |
Alkaloids
Anorexigenic Agents …
BCRP/ABCG2 Inhibitors
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Citalopram
Citalopram, Citalopramum
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DB00215 | small molecule |
Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of … |
Amines
Antidepressive Agents
Antidepressive Agents …
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Pregabalin
(S)-3-Isobutyl GABA, 3-Isobutyl GABA
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DB00230 | small molecule |
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter.[A173995] It may be used to manage neuropathic pain, … |
Acids, Acyclic
Agents causing …
Amino Acids
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Temazepam
Temazepam
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DB00231 | small molecule |
Temazepam, like many other similar and related benzodiazepines, acts as a gamma-aminobutyric acid (GABA) modulator and is capable of eliciting … |
Anti-Anxiety Agents
Benzazepines
Benzodiazepine hypnotics …
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Venlafaxine
Venlafaxina, Venlafaxine
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DB00285 | small molecule |
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, [desvenlafaxine], works by blocking the … |
Agents producing …
Agents that …
Amines
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Atomoxetine
(-)-Tomoxetine, Atomoxetina
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DB00289 | small molecule |
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known … |
Adrenergic Agents
Agents producing …
Agents that …
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Valproic acid
2-n-propyl-n-valeric acid, 2-propyl-pentanoic acid
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DB00313 | small molecule |
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton.[A178051] It … |
Acids, Acyclic
Anti-epileptic Agent
Anticonvulsants
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Acetaminophen
4-(Acetylamino)phenol, 4-acetamidophenol
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DB00316 | small molecule |
Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and is recommended as first-line therapy … |
Acetaminophen and …
Amides
Amines
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Olanzapine
2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine, Olanzapin
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DB00334 | small molecule |
Olanzapine is a thienobenzodiazepine derivative and an atypical or second-generation antipsychotic agent.[A176996] Its chemical structure contains a thieno[2,3-b][1,5]benzodiazepine core, and … |
Adrenergic alpha-1 …
Adrenergic alpha-Antagonists
Adrenergic Antagonists
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Omeprazole
OMEP, Omeprazol
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DB00338 | small molecule |
Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. These disorders … |
2-Pyridinylmethylsulfinylbenzimidazoles
Acid Reducers
Alimentary Tract …
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Mirtazapine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine, 6-Azamianserin
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DB00370 | small molecule |
Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in … |
Adrenergic Agents
Adrenergic alpha-2 …
Adrenergic alpha-Antagonists
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Alprazolam
8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine, Alprazolam
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DB00404 | small molecule |
Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders.[L34783, L34788] It is mainly metabolized by CYP3As … |
Amines
Anti-Anxiety Agents
Benzazepines
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Methylphenidate
Methyl phenidylacetate, methyl phenyl(piperidin-2-yl)acetate
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DB00422 | small molecule |
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. … |
Acids, Carbocyclic
Agents that …
Agents that …
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Zolpidem
N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide, Zolpidem
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DB00425 | small molecule |
Zolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. … |
Benzodiazepine hypnotics …
Central Nervous …
Central Nervous …
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Fluoxetine
(+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine, (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
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DB00472 | small molecule |
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).[A181673] It gained FDA approval in 1987 … |
Agents that …
Amines
Anticholinergic Agents
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Duloxetine
(3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine, (S)-duloxetine
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DB00476 | small molecule |
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly … |
Agents producing …
Analgesics
Antidepressive Agents
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Buspirone
8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione, Buspiron
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DB00490 | small molecule |
Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class,[A180991] … |
Agents that …
Antidepressive Agents
Azaspirodecanedione Derivatives
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Hydroxyzine
Hidroxizina, Hychotine
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DB00557 | small molecule |
Hydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589 |
Anti-Anxiety Agents
Antipruritics
Central Nervous …
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Trazodone
2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one, Trazodona
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DB00656 | small molecule |
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants.[A181180] It is used in … |
Adrenergic alpha-1 …
Adrenergic alpha-Antagonists
Adrenergic Antagonists
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Paroxetine
(−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine, (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine
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DB00715 | small molecule |
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including … |
Agents producing …
Anticholinergic Agents
Antidepressive Agents
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Risperidone
Risperidona, Risperidone
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DB00734 | small molecule |
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions … |
Adrenergic alpha-1 …
Adrenergic alpha-Antagonists
Adrenergic Antagonists
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Diazepam
7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, Diazepam
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DB00829 | small molecule |
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are … |
Adjuvants, Anesthesia
Anesthetics
Anesthetics, General
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Gabapentin
1-(Aminomethyl)cyclohexaneacetic acid, Gabapentin
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DB00996 | small molecule |
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the … |
Acids, Acyclic
Acids, Carbocyclic
Amines
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Ibuprofen
(±)-2-(p-isobutylphenyl)propionic acid, (±)-ibuprofen
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DB01050 | small molecule |
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.[A39074] … |
Acids, Carbocyclic
Agents causing …
Agents causing …
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Melatonin
5-methoxy-N-acetyl tryptamine, 5-methoxy-N-acetyltryptamine
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DB01065 | small molecule |
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is … |
Amines
Antioxidants
Biogenic Amines
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Clonazepam
1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one, 5-(2-chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one
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DB01068 | small molecule |
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may … |
Anticonvulsants
Benzazepines
Benzodiazepines and …
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Sertraline
(+)-Sertraline, (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
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DB01104 | small molecule |
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs … |
Agents that …
Amines
Antidepressive Agents
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Bupropion
Amfebutamone, Bupropion
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DB01156 | small molecule |
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management … |
Agents that …
Aminoketone Antidepressants
Antidepressive Agents
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Escitalopram
(+)-Citalopram, (S)-Citalopram
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DB01175 | small molecule |
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram].[A185420] It is used to restore serotonergic … |
Amines
Anticholinergic Agents
Antidepressive Agents
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Lurasidone
Lurasidona, Lurasidone
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DB08815 | small molecule |
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration … |
Adrenergic Agents
Adrenergic alpha-2 …
Adrenergic alpha-Antagonists
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Lithium carbonate
Carbonic acid, dilithium salt, Dilithium carbonate
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DB14509 | small molecule |
Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of … |
Acids
Acids, Noncarboxylic
Alkalies
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